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(max-width:1024px){.ArticleDetailsV4__asideLeft{grid-column:5/21}}@media only screen and (max-width:768px){.ArticleDetailsV4__asideLeft{grid-column:2/16}}@media only screen and (max-width:563px){.ArticleDetailsV4__asideLeft{grid-column:1/9}}.ArticleDetailsV4__asideLeft .ArticleLayoutHeader{display:none}@media only screen and (max-width:1024px){.ArticleDetailsV4__asideLeft .ArticleLayoutHeader{display:flex}.ArticleDetailsV4__asideLeft .ExpandablePanel{display:none}}.ArticleDetailsV4__main{grid-column:8/18;grid-row:2/3}@media only screen and (max-width:1441px){.ArticleDetailsV4__main{grid-column:8/20;margin-bottom:64px}}@media only screen and (max-width:1280px){.ArticleDetailsV4__main{grid-column:7/21}}@media only screen and (max-width:1024px){.ArticleDetailsV4__main{grid-column:5/21;grid-row:3/4;margin-bottom:64px;padding-bottom:48px}}@media only screen and (max-width:768px){.ArticleDetailsV4__main{grid-column:2/16}}@media only screen and 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and (max-width:563px){.ArticleDetailsV4__main__title{margin:16px 0}}.ArticleDetailsV4__main .Tag{bottom:6px;display:inline-flex;font-weight:600;line-height:normal;margin-top:8px;position:relative}.ArticleDetailsV4__main .PeopleList{border-top:1px solid var(--grey40);padding-top:24px}@media only screen and (max-width:1441px){.ArticleDetailsV4__main .AffiliationList{border-bottom:none;margin:16px 0}}.ArticleDetailsV4__main__divider{border-bottom:1px solid var(--grey40);margin-bottom:80px;padding-bottom:56px}@media only screen and (max-width:1441px){.ArticleDetailsV4__main__divider{margin-bottom:40px}}@media only screen and (max-width:563px){.ArticleDetailsV4__main__divider{padding-bottom:32px}}@media only screen and (max-width:1024px){.ArticleDetailsV4__main .ArticleLayoutHeader{display:none}}.ArticleDetailsV4__main .Tabs{gap:16px;margin-bottom:32px}@media only screen and (max-width:1024px){.ArticleDetailsV4__main .Tabs{margin-bottom:24px}}@media only screen and (max-width:563px){.ArticleDetailsV4__main .Tabs{margin-bottom:16px}}.ArticleDetailsV4__main__content .ArticleContent p .InlineGraphic{max-height:16px}.ArticleDetailsV4__main__content .ArticleContent ul li:last-child p:last-child{margin-bottom:0}.ArticleDetailsV4__main__content .ArticleContent ul[list-type=alpha-lower]{list-style:lower-alpha;margin-left:18px}.ArticleDetailsV4__main__content .ArticleContent ul[list-type=simple] li{display:block!important;gap:8px;padding-left:16px}.ArticleDetailsV4__main__content .ArticleContent ul[list-type=simple] li strong{display:inline-block;transform:translate(-16px);width:0}.ArticleDetailsV4__main__content .ArticleContent ul[list-type=simple] li strong+p{display:inline}.ArticleDetailsV4__main__content .ArticleContent ul:not([list-type]):not([class]) li{display:inline-flex;gap:8px}.ArticleDetailsV4__main__content .ArticleContent [content-type=algorithm] ul[list-type=simple] 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(max-width:1024px){.ArticleDetailsV4__articleType{font-size:.875rem;font-weight:700;line-height:1.25rem}}.ArticleDetailsV4__publication{display:flex;flex-direction:row;font-size:1rem;font-weight:300;line-height:1.375rem;row-gap:2px}@media only screen and (max-width:1024px){.ArticleDetailsV4__publication{font-size:.875rem;font-weight:300;line-height:1.25rem}}.ArticleDetailsV4__retraction{margin-top:32px}.ArticleDetailsV4__retraction a{color:var(--red50)}.ArticleDetailsV4__retraction a:hover{text-decoration:underline}.ArticleDetailsV4 h1:not([class]){font-size:1.5rem;font-weight:500;line-height:2.0625rem;margin:24px 0}@media (min-width:768px){.ArticleDetailsV4 h1:not([class]){font-size:1.75rem;font-weight:500;line-height:2.4375rem}}@media (min-width:1024px){.ArticleDetailsV4 h1:not([class]){font-size:1.75rem;font-weight:500;line-height:2.4375rem}}@media (min-width:1280px){.ArticleDetailsV4 h1:not([class]){font-size:2rem;font-weight:500;line-height:2.75rem}}@media (min-width:1440px){.ArticleDetailsV4 h1:not([class]){font-size:2rem;font-weight:500;line-height:2.75rem}}@media (min-width:1920px){.ArticleDetailsV4 h1:not([class]){font-size:2.5rem;font-weight:500;line-height:3.5rem}}@media only screen and (max-width:563px){.ArticleDetailsV4 h1:not([class]){margin:16px 0}}.ArticleDetailsV4 h1:not([class])+h2:not([class]){margin-top:24px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h1:not([class])+h2:not([class]){margin-top:16px}}.ArticleDetailsV4 h1:not([class])+:not(h2),.ArticleDetailsV4 h1:not([class])+p{margin-top:32px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h1:not([class])+:not(h2),.ArticleDetailsV4 h1:not([class])+p{margin-top:24px}}.ArticleDetailsV4 h2:not([class]){font-size:1.25rem;font-weight:500;line-height:1.75rem;margin-top:var(--spacing-vertical-xl)}@media (min-width:768px){.ArticleDetailsV4 h2:not([class]){font-size:1.5rem;font-weight:500;line-height:2.0625rem}}@media (min-width:1024px){.ArticleDetailsV4 h2:not([class]){font-size:1.5rem;font-weight:500;line-height:2.0625rem}}@media (min-width:1280px){.ArticleDetailsV4 h2:not([class]){font-size:1.75rem;font-weight:500;line-height:2.4375rem}}@media (min-width:1440px){.ArticleDetailsV4 h2:not([class]){font-size:1.75rem;font-weight:500;line-height:2.4375rem}}@media (min-width:1920px){.ArticleDetailsV4 h2:not([class]){font-size:2rem;font-weight:500;line-height:2.75rem}}.ArticleDetailsV4 h2:not([class])+h3:not([class]){margin-top:24px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h2:not([class])+h3:not([class]){margin-top:16px}}.ArticleDetailsV4 h2:not([class])+:not(h3),.ArticleDetailsV4 h2:not([class])+p{margin-top:32px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h2:not([class])+:not(h3),.ArticleDetailsV4 h2:not([class])+p{margin-top:24px}}.ArticleDetailsV4 h3:not([class]){font-size:1.125rem;font-weight:500;line-height:1.5625rem;margin-top:24px}@media (min-width:768px){.ArticleDetailsV4 h3:not([class]){font-size:1.125rem;font-weight:500;line-height:1.5625rem}}@media (min-width:1024px){.ArticleDetailsV4 h3:not([class]){font-size:1.125rem;font-weight:500;line-height:1.5625rem}}@media (min-width:1280px){.ArticleDetailsV4 h3:not([class]){font-size:1.5rem;font-weight:500;line-height:2.0625rem}}@media (min-width:1440px){.ArticleDetailsV4 h3:not([class]){font-size:1.5rem;font-weight:500;line-height:2.0625rem}}@media (min-width:1920px){.ArticleDetailsV4 h3:not([class]){font-size:1.5rem;font-weight:500;line-height:2.0625rem}}.ArticleDetailsV4 h3:not([class])+h4:not([class]){margin-top:16px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h3:not([class])+h4:not([class]){margin-top:8px}}.ArticleDetailsV4 h3:not([class])+:not(h4),.ArticleDetailsV4 h3:not([class])+p{margin-top:16px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h3:not([class])+:not(h4),.ArticleDetailsV4 h3:not([class])+p{margin-top:8px}}.ArticleDetailsV4 h4:not([class]){font-size:1rem;font-weight:500;line-height:1.375rem;margin-top:24px}@media (min-width:768px){.ArticleDetailsV4 h4:not([class]){font-size:1rem;font-weight:500;line-height:1.375rem}}@media (min-width:1024px){.ArticleDetailsV4 h4:not([class]){font-size:1rem;font-weight:500;line-height:1.375rem}}@media (min-width:1280px){.ArticleDetailsV4 h4:not([class]){font-size:1.25rem;font-weight:500;line-height:1.75rem}}@media (min-width:1440px){.ArticleDetailsV4 h4:not([class]){font-size:1.25rem;font-weight:500;line-height:1.75rem}}@media (min-width:1920px){.ArticleDetailsV4 h4:not([class]){font-size:1.25rem;font-weight:500;line-height:1.75rem}}@media only screen and (max-width:1024px){.ArticleDetailsV4 h4:not([class]){margin-top:16px}}.ArticleDetailsV4 h4:not([class])+h5:not([class]){margin-top:16px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h4:not([class])+h5:not([class]){margin-top:8px}}.ArticleDetailsV4 h4:not([class])+:not(h5),.ArticleDetailsV4 h4:not([class])+p{margin-top:16px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h4:not([class])+:not(h5),.ArticleDetailsV4 h4:not([class])+p{margin-top:8px}}.ArticleDetailsV4 h5:not([class]){font-size:.875rem;font-weight:700;line-height:1.25rem;margin-top:24px}@media (min-width:768px){.ArticleDetailsV4 h5:not([class]){font-size:.875rem;font-weight:700;line-height:1.25rem}}@media (min-width:1024px){.ArticleDetailsV4 h5:not([class]){font-size:.875rem;font-weight:700;line-height:1.25rem}}@media (min-width:1280px){.ArticleDetailsV4 h5:not([class]){font-size:1.125rem;font-weight:700;line-height:1.5625rem}}@media (min-width:1440px){.ArticleDetailsV4 h5:not([class]){font-size:1.125rem;font-weight:700;line-height:1.5625rem}}@media (min-width:1920px){.ArticleDetailsV4 h5:not([class]){font-size:1.125rem;font-weight:700;line-height:1.5625rem}}@media only screen and (max-width:1024px){.ArticleDetailsV4 h5:not([class]){margin-top:16px}}.ArticleDetailsV4 h5:not([class])+h6:not([class]){margin-top:16px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h5:not([class])+h6:not([class]){margin-top:8px}}.ArticleDetailsV4 h5:not([class])+p{margin-top:8px}@media only screen and (max-width:1024px){.ArticleDetailsV4 h5:not([class])+p{margin-top:0}}.ArticleDetailsV4 h6:not([class]){font-size:.875rem;font-weight:500;line-height:1.25rem;margin-top:24px}@media (min-width:768px){.ArticleDetailsV4 h6:not([class]){font-size:.875rem;font-weight:500;line-height:1.25rem}}@media (min-width:1024px){.ArticleDetailsV4 h6:not([class]){font-size:.875rem;font-weight:500;line-height:1.25rem}}@media (min-width:1280px){.ArticleDetailsV4 h6:not([class]){font-size:1.125rem;font-weight:500;line-height:1.5625rem}}@media (min-width:1440px){.ArticleDetailsV4 h6:not([class]){font-size:1.125rem;font-weight:500;line-height:1.5625rem}}@media (min-width:1920px){.ArticleDetailsV4 h6:not([class]){font-size:1.125rem;font-weight:500;line-height:1.5625rem}}@media only screen and (max-width:1024px){.ArticleDetailsV4 h6:not([class]){margin-top:16px}}.ArticleDetailsV4 h6:not([class])+p{margin-top:0}@media only screen and (max-width:1024px){.ArticleDetailsV4 h6:not([class])+p{margin-top:0}}.ArticleDetailsV4 sup{display:inline-block;margin-left:1px;transform:translateY(-5px);vertical-align:baseline}.ArticleDetailsV4 ul[list-type=bullet]{list-style:disc;margin-left:1rem}.ArticleDetailsV4 ul[list-type=bullet] ul[list-type=bullet]{list-style:circle;margin-left:0}.ArticleDetailsV4 ul[list-type=order]{list-style:decimal;margin-left:1rem}.ArticleDetailsV4 p.Statement,.ArticleDetailsV4 p[class=RelatedArticle],.ArticleDetailsV4 p[class=notranslate],.ArticleDetailsV4 pre{font-size:1rem;font-weight:300;line-height:1.375rem;margin-bottom:16px}.Summary a,b,strong{font-weight:700}.Summary a{color:var(--maincolor50);cursor:pointer;position:relative;text-decoration:none;transition:color .3s cubic-bezier(.37,.74,.15,1);word-break:break-word}.Summary a:hover{color:var(--maincolor70);text-decoration:underline;text-decoration-thickness:1px;text-underline-offset:2px}