AUTHOR=Dong Fan , Hardy Barry , Liu Jie , Mohoric Tomaz , Guo Wenjing , Exner Thomas , Tong Weida , Dohler Joh , Bachler Daniel , Hong Huixiao 

TITLE=Development of a comprehensive open access “molecules with androgenic activity resource (MAAR)” to facilitate risk assessment of chemicals

JOURNAL=Experimental Biology and Medicine

VOLUME=Volume 249 - 2024

YEAR=2024

URL=https://www.ebm-journal.org/journals/experimental-biology-and-medicine/articles/10.3389/ebm.2024.10279

DOI=10.3389/ebm.2024.10279

ISSN=1535-3699

ABSTRACT=The prevalence of endocrine-disrupting chemicals (EDCs) and their potential health impacts necessitate robust tools for risk assessment. The androgen receptor is crucial in mediating the effects of male sex hormones, with disruption during critical developmental periods leading to reproductive health issues. To address this, the Molecules with Androgenic Activity Resource (MAAR) was developed. MAAR integrates diverse data sources to create an open-access platform facilitating chemical risk assessment. By offering easy navigation and extraction of androgenic activity data, MAAR enhances transparency and collaboration in addressing the challenges posed by androgenic EDCs.