Experimental Biology and Medicine | New and Recent Articles https://www.ebm-journal.org/journals/experimental-biology-and-medicine RSS Feed for Experimental Biology and Medicine | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-04-17T02:16:08.165+00:00 60 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11021 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11021 <![CDATA[CAR T cell engineering approaches to minimise toxicities]]> 2026-04-15T00:00:00Z Mini Review Elizabeth HogbenAnna SchurichCharlotte Graham https://www.ebm-journal.org/articles/10.3389/ebm.2026.10850 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10850 <![CDATA[Lymphatic pumping technique in mice alters blood parameters and metastatic melanoma in an age-dependent manner]]> 2026-03-30T00:00:00Z Original Research Christopher WalshMatthew KirsteinElise WagnerEmily ScottJerome WalshShashank ReddyNathan HoggardArshad AhmadReetobrata BasuSam MathesYanrong QianJohn J. Kopchick https://www.ebm-journal.org/articles/10.3389/ebm.2026.10857 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10857 <![CDATA[Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice]]> 2026-03-20T00:00:00Z Original Research Elle KoivunotkoJulia MonolaChris S. PridgeonJere LindenRiina HarjumäkiEmrah YatkinMari MadetojaMarjo Yliperttula https://www.ebm-journal.org/articles/10.3389/ebm.2026.10933 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10933 <![CDATA[Genetics of epilepsy]]> 2026-03-19T00:00:00Z Review Kynen PiacentiniAthanasios GaitatzisSulev Kõks https://www.ebm-journal.org/articles/10.3389/ebm.2026.10907 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10907 <![CDATA[A novel platelet-rich plasma clinically induces reliable, rapid, long-term chronic peripheral neuropathic pain elimination]]> 2026-03-13T00:00:00Z Brief Communication Damien P. KufflerOnix ReyesIvan J. SosaChristian A. Foy https://www.ebm-journal.org/articles/10.3389/ebm.2026.10796 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10796 <![CDATA[Enhanced oxidative stress resilience in C. elegans acox-1.1 mutants through CTL-3 and proteasomal regulation]]> 2026-03-13T00:00:00Z Brief Communication Woori BaeMina NormanMyon Hee Lee https://www.ebm-journal.org/articles/10.3389/ebm.2026.10679 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10679 <![CDATA[Low dose thirdhand smoke exposure enhances platelet functional responses in mice]]> 2026-03-12T00:00:00Z Original Research Precious O. BadejoAhmed B. AlarabiHamdy E. A. AliLanam MillicanReina De La PazShelby S. UmphresSadia KamalFatima Z. AlshboolFadi T. Khasawneh https://www.ebm-journal.org/articles/10.3389/ebm.2026.10867 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10867 <![CDATA[Metabolomics-guided identification of bioactive phytometabolites from South African plants targeting neuroblastoma]]> 2026-03-05T00:00:00Z Original Research Mmei Cheryl MotshudiClarissa Marcelle NaidooChikwelu Lawrence ObiBenson Chucks IwerieborEarl PrinslooMuhammad Sulaiman ZubairNqobile Monate Mkolo https://www.ebm-journal.org/articles/10.3389/ebm.2026.10929 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10929 <![CDATA[Global MyoG research 2004–2024: a bibliometric analysis of trends and translational implications]]> 2026-03-05T00:00:00Z Original Research Luoming HuWeizhong ZhuangWeimin ChenSong YangShuo ChenXin WangQiang GaoJimei Chen https://www.ebm-journal.org/articles/10.3389/ebm.2026.10834 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10834 <![CDATA[A novel de novo ATP2B1 variant causes autosomal dominant intellectual developmental disorder 66 by disrupting calcium homeostasis via impaired membrane trafficking]]> 2026-03-03T00:00:00Z Original Research Huanhuan ZangXiaoyun YangYucai LiuCaiyun MaDawei Yang C, p.Thr714Pro) in the proband. The proband presented with infantile spasms, GDD (Gesell Developmental Quotient: 65–74), and severe growth restriction (height/weight <−2 SD). To investigate the variant’s pathogenicity, the wild-type (WT) and mutant ATP2B1 constructs, N-terminally tagged with mScarlet, were transfected into HEK293T cells. Confocal imaging demonstrated profound cytoplasmic mislocalization of the p.Thr714Pro mutant protein, contrasting sharply with the characteristic plasma membrane localization of WT ATP2B1. Measurement of intracellular Ca2+ levels using Fluo-4 AM showed a significant 2.07-fold increase in basal Ca2+ levels in cells expressing the mutant compared to WT. This finding expands the spectrum of ATP2B1 variants associated with MRD66 and confirms calcium dyshomeostasis as the core pathomechanism. This case of MRD66 demonstrates a very early onset of seizures, consistent with the recognized phenotypic variability and the critical role of PMCA1 in early neurodevelopment.]]> https://www.ebm-journal.org/articles/10.3389/ebm.2026.10701 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10701 <![CDATA[Ananalysis of the effects of Treg cell therapy intervention on the gut microbiota of type 1 diabetic mice using 16S rRNA gene sequencing]]> 2026-03-03T00:00:00Z Original Research Mengyao ZhouKang DuHanmin WangZhuxian ZhangRui ZhaoChenghong MaQionger HuangWei ZhangWeiwen Chen https://www.ebm-journal.org/articles/10.3389/ebm.2026.10709 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10709 <![CDATA[Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validation]]> 2026-03-02T00:00:00Z Original Research Xiqin WangChrismis Novalinda GintingWilliam Leslie https://www.ebm-journal.org/articles/10.3389/ebm.2026.10835 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10835 <![CDATA[Skeletal muscle reprogramming in peripheral nerve injury: mechanisms, therapeutic roles, and complication management]]> 2026-03-02T00:00:00Z Review Fuqiang LongXiaoru PanAnxin HeXinlu WangZairong WeiShaoying Gao https://www.ebm-journal.org/articles/10.3389/ebm.2026.10755 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10755 <![CDATA[L-Glutamine attenuates peritoneal fibrosis developed in 5-Fluorouracil-treated mice]]> 2026-02-24T00:00:00Z Original Research Juliana Francisca Grossi HelenoLeticia Cristine Cardoso dos SantosIgor Campos FontesMirielly Ranny Almeida Paiva SilvaLucas Barbosa CorreiaNayma Drielly Granato SilvaPedro Henrique Dias Moura PrazeresPedro Pires Goulart GuimarãesDerek W. GilroySilvia Passos AndradePaula Peixoto Campos https://www.ebm-journal.org/articles/10.3389/ebm.2026.10788 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10788 <![CDATA[Intra- and extrapulmonary lipopolysaccharides-induced acute lung injury and pharmacotherapeutic response patterns in ventilated 7-day-old rabbits]]> 2026-02-24T00:00:00Z Original Research Guiyin ZhuangQiang GuSiyu XieXiaojing GuoBo Sun https://www.ebm-journal.org/articles/10.3389/ebm.2026.10894 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10894 <![CDATA[The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals]]> 2026-02-23T00:00:00Z Brief Communication Inna BurakovaYuliya SmirnovaPolina MorozovaSvetlana PogorelovaOlga KryukovaTatiana KislovaOlga KorneevaMikhail Syromyatnikov https://www.ebm-journal.org/articles/10.3389/ebm.2026.10847 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10847 <![CDATA[The gut-retina axis in age-related macular degeneration: immune crosstalk and metabolite production]]> 2026-02-23T00:00:00Z Mini Review Beryl ZhouZaid ParekhChristopher PhungSarah H. RodriguezDimitra Skondra https://www.ebm-journal.org/articles/10.3389/ebm.2026.10745 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10745 <![CDATA[Poliovirus receptor (PVR) expression as a predictor of relapse in colorectal cancer: bioinformatics and virtual screening]]> 2026-02-13T00:00:00Z Original Research Sulaiman S. AlhudaithiMuhamed Hamza R. SalihZaid H. AlHusseiniSarah M. AlmufadhiliNoura AlelayaniAhmed H. BakheitHamad M. AlkahtaniHanadi H. AsiriAli A. AlshamraniAli R. AlhoshaniMoureq R. AlotaibiHomood M. As Sobeai https://www.ebm-journal.org/articles/10.3389/ebm.2026.10712 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10712 <![CDATA[Electrotherapy in the management of neuropathic corneal pain: narrative review]]> 2026-02-06T00:00:00Z Review A. V. ShanmathiMingyi YuChang LiuIsabelle Xin Yu LeeLouis TongYu-Chi Liu https://www.ebm-journal.org/articles/10.3389/ebm.2026.10938 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10938 <![CDATA[How can we balance risk and benefit of interleukin-18 armored T cell therapies?]]> 2026-02-06T00:00:00Z Mini Review Paulina VicenovaJohn Maher