Experimental Biology and Medicine | New and Recent Articles https://www.ebm-journal.org/journals/experimental-biology-and-medicine RSS Feed for Experimental Biology and Medicine | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-05-14T02:16:14.734+00:00 60 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10987 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10987 <![CDATA[Peripheral immune cells and glycation indices as potential diagnostic biomarkers in amyotrophic lateral sclerosis]]> 2026-05-13T00:00:00Z Original Research Xue YangJing YangRui LiHui DongYaling Liu https://www.ebm-journal.org/articles/10.3389/ebm.2026.10945 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10945 <![CDATA[Antibody-mediated immune responses and cardiovascular disease: a Mendelian randomization study]]> 2026-05-12T00:00:00Z Original Research Yi LiJiuqi FanLirong Wu https://www.ebm-journal.org/articles/10.3389/ebm.2026.10922 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10922 <![CDATA[Causal relationship between oral diseases and hypertension: a Mendelian randomization study]]> 2026-05-07T00:00:00Z Original Research Bofan QianZhiwen Fang https://www.ebm-journal.org/articles/10.3389/ebm.2026.10997 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10997 <![CDATA[Ferroptosis and futile recanalization after mechanical thrombectomy in acute ischemic stroke: mechanisms, risk factors, predictive models and therapeutic interventions]]> 2026-05-01T00:00:00Z Review Yuexin WuCuiying ZhangYangyang PengLonglong Liu https://www.ebm-journal.org/articles/10.3389/ebm.2026.10946 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10946 <![CDATA[Sacubitril valsartan combined with bisoprolol reduces doxorubicin-induced cardiotoxicity in rats by attenuating oxidative stress]]> 2026-04-28T00:00:00Z Original Research Ping LiuHui YangRunqi LiHui HuangMin Xu https://www.ebm-journal.org/articles/10.3389/ebm.2026.10988 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10988 <![CDATA[Training the next-generation of biomedical scientists through artificial intelligence-driven education and research in pharmacology and pharmaceutical sciences]]> 2026-04-22T00:00:00Z Mini Review Santosh KumarRitu KarwasraWeinan ZhouJayaraman SeetharamanBhupesh Singla https://www.ebm-journal.org/articles/10.3389/ebm.2026.10827 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10827 <![CDATA[Elevated ApoC3 levels in cerebrospinal fluid predict poor outcomes in patients with aneurysmal subarachnoid hemorrhage]]> 2026-04-17T00:00:00Z Original Research Bin TongJunjie WangJiarui ChenQia ZhangZhouhan XuKaichuang YangXiaomin Chen https://www.ebm-journal.org/articles/10.3389/ebm.2026.11021 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11021 <![CDATA[CAR T cell engineering approaches to minimise toxicities]]> 2026-04-15T00:00:00Z Mini Review Elizabeth HogbenAnna SchurichCharlotte Graham https://www.ebm-journal.org/articles/10.3389/ebm.2026.10850 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10850 <![CDATA[Lymphatic pumping technique in mice alters blood parameters and metastatic melanoma in an age-dependent manner]]> 2026-03-30T00:00:00Z Original Research Christopher WalshMatthew KirsteinElise WagnerEmily ScottJerome WalshShashank ReddyNathan HoggardArshad AhmadReetobrata BasuSam MathesYanrong QianJohn J. Kopchick https://www.ebm-journal.org/articles/10.3389/ebm.2026.10857 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10857 <![CDATA[Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice]]> 2026-03-20T00:00:00Z Original Research Elle KoivunotkoJulia MonolaChris S. PridgeonJere LindenRiina HarjumäkiEmrah YatkinMari MadetojaMarjo Yliperttula https://www.ebm-journal.org/articles/10.3389/ebm.2026.10933 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10933 <![CDATA[Genetics of epilepsy]]> 2026-03-19T00:00:00Z Review Kynen PiacentiniAthanasios GaitatzisSulev Kõks https://www.ebm-journal.org/articles/10.3389/ebm.2026.10907 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10907 <![CDATA[A novel platelet-rich plasma clinically induces reliable, rapid, long-term chronic peripheral neuropathic pain elimination]]> 2026-03-13T00:00:00Z Brief Communication Damien P. KufflerOnix ReyesIvan J. SosaChristian A. Foy https://www.ebm-journal.org/articles/10.3389/ebm.2026.10796 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10796 <![CDATA[Enhanced oxidative stress resilience in C. elegans acox-1.1 mutants through CTL-3 and proteasomal regulation]]> 2026-03-13T00:00:00Z Brief Communication Woori BaeMina NormanMyon Hee Lee https://www.ebm-journal.org/articles/10.3389/ebm.2026.10679 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10679 <![CDATA[Low dose thirdhand smoke exposure enhances platelet functional responses in mice]]> 2026-03-12T00:00:00Z Original Research Precious O. BadejoAhmed B. AlarabiHamdy E. A. AliLanam MillicanReina De La PazShelby S. UmphresSadia KamalFatima Z. AlshboolFadi T. Khasawneh https://www.ebm-journal.org/articles/10.3389/ebm.2026.10867 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10867 <![CDATA[Metabolomics-guided identification of bioactive phytometabolites from South African plants targeting neuroblastoma]]> 2026-03-05T00:00:00Z Original Research Mmei Cheryl MotshudiClarissa Marcelle NaidooChikwelu Lawrence ObiBenson Chucks IwerieborEarl PrinslooMuhammad Sulaiman ZubairNqobile Monate Mkolo https://www.ebm-journal.org/articles/10.3389/ebm.2026.10929 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10929 <![CDATA[Global MyoG research 2004–2024: a bibliometric analysis of trends and translational implications]]> 2026-03-05T00:00:00Z Original Research Luoming HuWeizhong ZhuangWeimin ChenSong YangShuo ChenXin WangQiang GaoJimei Chen https://www.ebm-journal.org/articles/10.3389/ebm.2026.10701 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10701 <![CDATA[Ananalysis of the effects of Treg cell therapy intervention on the gut microbiota of type 1 diabetic mice using 16S rRNA gene sequencing]]> 2026-03-03T00:00:00Z Original Research Mengyao ZhouKang DuHanmin WangZhuxian ZhangRui ZhaoChenghong MaQionger HuangWei ZhangWeiwen Chen https://www.ebm-journal.org/articles/10.3389/ebm.2026.10834 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10834 <![CDATA[A novel de novo ATP2B1 variant causes autosomal dominant intellectual developmental disorder 66 by disrupting calcium homeostasis via impaired membrane trafficking]]> 2026-03-03T00:00:00Z Original Research Huanhuan ZangXiaoyun YangYucai LiuCaiyun MaDawei Yang C, p.Thr714Pro) in the proband. The proband presented with infantile spasms, GDD (Gesell Developmental Quotient: 65–74), and severe growth restriction (height/weight <−2 SD). To investigate the variant’s pathogenicity, the wild-type (WT) and mutant ATP2B1 constructs, N-terminally tagged with mScarlet, were transfected into HEK293T cells. Confocal imaging demonstrated profound cytoplasmic mislocalization of the p.Thr714Pro mutant protein, contrasting sharply with the characteristic plasma membrane localization of WT ATP2B1. Measurement of intracellular Ca2+ levels using Fluo-4 AM showed a significant 2.07-fold increase in basal Ca2+ levels in cells expressing the mutant compared to WT. This finding expands the spectrum of ATP2B1 variants associated with MRD66 and confirms calcium dyshomeostasis as the core pathomechanism. This case of MRD66 demonstrates a very early onset of seizures, consistent with the recognized phenotypic variability and the critical role of PMCA1 in early neurodevelopment.]]> https://www.ebm-journal.org/articles/10.3389/ebm.2026.10835 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10835 <![CDATA[Skeletal muscle reprogramming in peripheral nerve injury: mechanisms, therapeutic roles, and complication management]]> 2026-03-02T00:00:00Z Review Fuqiang LongXiaoru PanAnxin HeXinlu WangZairong WeiShaoying Gao https://www.ebm-journal.org/articles/10.3389/ebm.2026.10709 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10709 <![CDATA[Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validation]]> 2026-03-02T00:00:00Z Original Research Xiqin WangChrismis Novalinda GintingWilliam Leslie