https://www.ebm-journal.org/journals/experimental-biology-and-medicine RSS Feed for Experimental Biology and Medicine | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-10-15T22:15:34.251+00:00 60 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11228 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11228 2026-10-14T00:00:00Z Original Research Júlia Nicoliello Pereira de CastroAna Rafaela Carvalho MonteAna Carolina Rodrigues de OliveiraJulia Dezordi AcacioThiago Adalton Rosa RodriguesMirella Telles Salgueiro BarboniAndré Maurício Passos LiberDaniela Maria Oliveira BonciDora Fix VenturaFernando Ferreira CostaAna Carolina Lima CamargoMônica Barbosa de Melo https://www.ebm-journal.org/articles/10.3389/ebm.2026.11329 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11329 2026-10-09T00:00:00Z Review Ruyue WangMenglin RenYuanjian XuYan SunZenghui Xu https://www.ebm-journal.org/articles/10.3389/ebm.2026.11244 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11244 2026-09-28T00:00:00Z Review Debdeep ChattopadhyayRamya Lakshmi RajendranNida MubinDurva TendulkarThoudam Debraj SinghSubhrojyoti GhoshSaurabh Kumar JhaPrakash GangadaranByeong-Cheol Ahn https://www.ebm-journal.org/articles/10.3389/ebm.2026.11165 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11165 2026-09-28T00:00:00Z Original Research Irem AkyelGraham K. Sheridan https://www.ebm-journal.org/articles/10.3389/ebm.2026.10935 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10935 2026-09-23T00:00:00Z Original Research E. S. YasakiM. V. SallesF. L. MottaJ. M. F. Sallum T (p.Arg283) nonsense variant in exon 6 was the most common variant in this cohort, identified in 24 homozygous out of 52 individuals and in 12 compound heterozygous. The phenotype of CERKL-related IRD is CORD with an early age of presentation and fast decrease in visual acuity. In addition to OMIM classifying this gene as an retinitis pigmentosa IRD, we believe CERKL has CORD phenotype, in concordance with evidence described in the literature.]]> https://www.ebm-journal.org/articles/10.3389/ebm.2026.10940 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10940 2026-09-17T00:00:00Z Original Research Mingyi YangJiale XieJing HuPengfei WenLin LiuZhi YangMing ZhangChangliang ZhuYani Su 0.003, OR 95% CI = 0.788 [0.672–0.924]), whereas no significant effect was detected from CD on PBC (P = 0.431, OR 95% CI = 0.956 [0.856–1.068]). We then extended the analysis to the overall IBD phenotype. The forward MR demonstrated a significant positive genetic relationship between PBC on IBD (P < 0.001, OR 95% CI = 1.076 [1.042–1.110]). Conversely, the reverse MR did not support a causal effect of IBD on PBC (P = 0.357, OR 95% CI = 0.898 [0.714–1.129]). The robustness of all these findings was confirmed by comprehensive sensitivity analyses, which showed no evidence of heterogeneity, horizontal pleiotropy, or undue influence from individual instrumental variables. Our MR analysis demonstrates that PBC serves as a genetic determinant of IBD as a whole and of UC/CD separately, whereas reverse causation is limited to a protective effect of UC on PBC. This direction-dependent and subtype-specific causal architecture provides novel insights into the shared etiological pathways between PBC and IBD.]]> https://www.ebm-journal.org/articles/10.3389/ebm.2026.11238 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11238 2026-09-16T00:00:00Z Original Research Xinwei ZhangWenyu XuZhou LiuJinan ZhangXiaorong Yang https://www.ebm-journal.org/articles/10.3389/ebm.2026.11023 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11023 2026-09-10T00:00:00Z Original Research Yutong ChengQiuai ShuZiwei WangJian WuYuxin PengJiale XieXiru LiangZhiwei TaoHaitao ShiZhongcao WeiJinhai WangNing Xie https://www.ebm-journal.org/articles/10.3389/ebm.2026.11199 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11199 2026-09-01T00:00:00Z Review Heyu MengJianjun RuanQing WangFanbo Meng https://www.ebm-journal.org/articles/10.3389/ebm.2026.11246 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11246 2026-08-28T00:00:00Z Review Huibo MaZongyou XieYihang CaiFangda LiJianqiang WuYuehong Zheng https://www.ebm-journal.org/articles/10.3389/ebm.2026.11146 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11146 2026-08-27T00:00:00Z Review Sihan YangZijun ZhangQing LiaoQipeng OuyangYongyou YeWei LuZhendong Jiang https://www.ebm-journal.org/articles/10.3389/ebm.2026.11144 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11144 2026-08-26T00:00:00Z Original Research Most. Humayra Binta RashidMehedi IslamSardar Mohammad Ashraful IslamMd. Rabiul Islam https://www.ebm-journal.org/articles/10.3389/ebm.2026.10915 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10915 2026-08-11T00:00:00Z Original Research Hongxia GuHuisheng Wu https://www.ebm-journal.org/articles/10.3389/ebm.2026.10902 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10902 2026-08-11T00:00:00Z Review Muriel W. LambertW. Clark Lambert https://www.ebm-journal.org/articles/10.3389/ebm.2026.11192 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11192 2026-08-06T00:00:00Z Review Baixian HuangQixin YangRuixue WangChaochao Zhao https://www.ebm-journal.org/articles/10.3389/ebm.2026.10958 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10958 2026-08-03T00:00:00Z Correction EBM Production Office https://www.ebm-journal.org/articles/10.3389/ebm.2026.10923 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10923 2026-07-27T00:00:00Z Original Research Juan JinQian PuChengrong WuYu LeiYaxin HuXiuju YangJinghui HuangFangfang WuLi XiaoLei Yu https://www.ebm-journal.org/articles/10.3389/ebm.2026.11114 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11114 2026-07-17T00:00:00Z Review Jianshu WangJunxuan XuZilu CuiJing Wu https://www.ebm-journal.org/articles/10.3389/ebm.2026.10948 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10948 2026-07-13T00:00:00Z Original Research Huan CaiZhenchun HuangJialin LiangHao ZhangZhonghua Liu https://www.ebm-journal.org/articles/10.3389/ebm.2026.11058 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11058 2026-07-10T00:00:00Z Review Shengyue JinMenglei ZhuYiyang LuJia ZhaoJiayi ZhuXiaohong Fang