Experimental Biology and Medicine | New and Recent Articles https://www.ebm-journal.org/journals/experimental-biology-and-medicine RSS Feed for Experimental Biology and Medicine | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-11-04T23:52:02.39+00:00 60 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11173 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11173 <![CDATA[Independent associations of gluteofemoral fat depots with hepatocellular carcinoma and the mediating role of the plasma lipidome: a mendelian randomization study]]> 2026-11-02T00:00:00Z Original Research Hang LiuFuming WangJinming TianRong LuoJianan ZhangXu JiangJijin Yang https://www.ebm-journal.org/articles/10.3389/ebm.2026.11213 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11213 <![CDATA[Multi-class classification of central and non-central geographic atrophy using optical coherence tomography]]> 2026-11-02T00:00:00Z Original Research Sadia SirazHindolo KamandaSina GholamiAhammed Sakir NabilNitya Tangada RaoSally S. OngMinhaj Nur Alam https://www.ebm-journal.org/articles/10.3389/ebm.2026.11455 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11455 <![CDATA[Correction: Sickle cell retinopathy molecular investigation through proteomic analysis of Townes HbSS mice retinas]]> 2026-11-02T00:00:00Z Correction Júlia Nicoliello Pereira de CastroAna Rafaela Carvalho MonteAna Carolina Rodrigues de OliveiraJulia Dezordi AcacioThiago Adalton Rosa RodriguesMirella Telles Salgueiro BarboniAndré Maurício Passos LiberDaniela Maria Oliveira BonciDora Fix VenturaFernando Ferreira CostaAna Carolina Lima CamargoMônica Barbosa de Melo https://www.ebm-journal.org/articles/10.3389/ebm.2026.11350 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11350 <![CDATA[SEL1L: molecular gatekeeper of the endoplasmic reticulum quality control network]]> 2026-10-30T00:00:00Z Review Zhenxuan ShenYiting NiuHedong ChenMeikun PanFan YangMeiying LiChong ZhangYali ZhouJianguo Yan https://www.ebm-journal.org/articles/10.3389/ebm.2026.11233 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11233 <![CDATA[Oral colchicine improves shoulder motion and reduces capsular fibrosis in a rat frozen shoulder model]]> 2026-10-28T00:00:00Z Original Research Gökay EkenAdnan KantarciTeoman AticiAhmet AkkocSelcan Akesen https://www.ebm-journal.org/articles/10.3389/ebm.2026.11373 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11373 <![CDATA[Epigenetic reprogramming of NK cell-mediated antitumor immunity in urothelial carcinoma: a mini-review]]> 2026-10-28T00:00:00Z Mini Review Himani KumariChih-Chieh ChouYu-Ting LeeCheng-Huang ShenMichael W. Y. Chan https://www.ebm-journal.org/articles/10.3389/ebm.2026.11196 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11196 <![CDATA[CLEC4E deletion in cardiac resident cells reduces infarct size and improves cardiac remodeling following myocardial ischemia-reperfusion injury]]> 2026-10-26T00:00:00Z Original Research Michiel AlgoetMing WuHilde GillijnsMatic PusovnikEllen CaluweKasia BlazejczykWilly GsellLotte GeerkensSenne De GrooteTatiana KuznetsovaUwe HimmelreichWouter OosterlinckStefan Janssens https://www.ebm-journal.org/articles/10.3389/ebm.2026.11307 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11307 <![CDATA[Correction: Bioinformatics and systems biology approach to identify the pathogenetic link of neurological pain and major depressive disorder]]> 2026-10-26T00:00:00Z Correction Jinjing HuJia FuYuxin CaiShuping ChenMengjian QuLisha ZhangWeichao FanZiyi WangQing ZengJihua Zou https://www.ebm-journal.org/articles/10.3389/ebm.2026.11091 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11091 <![CDATA[Ultrasound-guided platelet-rich plasma injection for peripheral nerve injury: a retrospective exploratory study]]> 2026-10-26T00:00:00Z Original Research Juanjuan HeLi JiangAnna TuNa LiHongyan ZhuYing LuXiaomei Wei https://www.ebm-journal.org/articles/10.3389/ebm.2026.11228 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11228 <![CDATA[Sickle cell retinopathy molecular investigation through proteomic analysis of Townes HbSS mice retinas]]> 2026-10-14T00:00:00Z Original Research Júlia Nicoliello Pereira de CastroAna Rafaela Carvalho MonteAna Carolina Rodrigues de OliveiraJulia Dezordi AcacioThiago Adalton Rosa RodriguesMirella Telles Salgueiro BarboniAndré Maurício Passos LiberDaniela Maria Oliveira BonciDora Fix VenturaFernando Ferreira CostaAna Carolina Lima CamargoMônica Barbosa de Melo https://www.ebm-journal.org/articles/10.3389/ebm.2026.11329 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11329 <![CDATA[Application of natural products combined with plant-derived extracellular vesicles in cancer therapy]]> 2026-10-09T00:00:00Z Review Ruyue WangMenglin RenYuanjian XuYan SunZenghui Xu https://www.ebm-journal.org/articles/10.3389/ebm.2026.11244 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11244 <![CDATA[Mitochondrial metabolic plasticity in cancer: hybrid bioenergetic states and translational targeting in surgical oncology]]> 2026-09-28T00:00:00Z Review Debdeep ChattopadhyayRamya Lakshmi RajendranNida MubinDurva TendulkarThoudam Debraj SinghSubhrojyoti GhoshSaurabh Kumar JhaPrakash GangadaranByeong-Cheol Ahn https://www.ebm-journal.org/articles/10.3389/ebm.2026.11165 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11165 <![CDATA[Refined protocol for quantifying hippocampal neurogenesis in organotypic slice cultures]]> 2026-09-28T00:00:00Z Original Research Irem AkyelGraham K. Sheridan https://www.ebm-journal.org/articles/10.3389/ebm.2026.10935 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10935 <![CDATA[CERKL-related inherited retinal dystrophy in a Brazilian cohort: genotype-phenotype correlation]]> 2026-09-23T00:00:00Z Original Research E. S. YasakiM. V. SallesF. L. MottaJ. M. F. Sallum T (p.Arg283) nonsense variant in exon 6 was the most common variant in this cohort, identified in 24 homozygous out of 52 individuals and in 12 compound heterozygous. The phenotype of CERKL-related IRD is CORD with an early age of presentation and fast decrease in visual acuity. In addition to OMIM classifying this gene as an retinitis pigmentosa IRD, we believe CERKL has CORD phenotype, in concordance with evidence described in the literature.]]> https://www.ebm-journal.org/articles/10.3389/ebm.2026.10940 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10940 <![CDATA[Primary biliary cirrhosis and inflammatory bowel disease: a two-sample bidirectional Mendelian randomization study]]> 2026-09-17T00:00:00Z Original Research Mingyi YangJiale XieJing HuPengfei WenLin LiuZhi YangMing ZhangChangliang ZhuYani Su 0.003, OR 95% CI = 0.788 [0.672–0.924]), whereas no significant effect was detected from CD on PBC (P = 0.431, OR 95% CI = 0.956 [0.856–1.068]). We then extended the analysis to the overall IBD phenotype. The forward MR demonstrated a significant positive genetic relationship between PBC on IBD (P < 0.001, OR 95% CI = 1.076 [1.042–1.110]). Conversely, the reverse MR did not support a causal effect of IBD on PBC (P = 0.357, OR 95% CI = 0.898 [0.714–1.129]). The robustness of all these findings was confirmed by comprehensive sensitivity analyses, which showed no evidence of heterogeneity, horizontal pleiotropy, or undue influence from individual instrumental variables. Our MR analysis demonstrates that PBC serves as a genetic determinant of IBD as a whole and of UC/CD separately, whereas reverse causation is limited to a protective effect of UC on PBC. This direction-dependent and subtype-specific causal architecture provides novel insights into the shared etiological pathways between PBC and IBD.]]> https://www.ebm-journal.org/articles/10.3389/ebm.2026.11238 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11238 <![CDATA[The causal relationship between antibody-mediated immune responses to infections and Graves’ disease: a bi-directional Mendelian randomization analysis]]> 2026-09-16T00:00:00Z Original Research Xinwei ZhangWenyu XuZhou LiuJinan ZhangXiaorong Yang https://www.ebm-journal.org/articles/10.3389/ebm.2026.11023 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11023 <![CDATA[Causal effects of gut microbiota on functional gastrointestinal disorders: a bidirectional Mendelian randomization study]]> 2026-09-10T00:00:00Z Original Research Yutong ChengQiuai ShuZiwei WangJian WuYuxin PengJiale XieXiru LiangZhiwei TaoHaitao ShiZhongcao WeiJinhai WangNing Xie https://www.ebm-journal.org/articles/10.3389/ebm.2026.11199 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11199 <![CDATA[Maternal high-fat diet and risk of cardiovascular disease in offspring: a review of mechanisms, controversies, and interventions]]> 2026-09-01T00:00:00Z Review Heyu MengJianjun RuanQing WangFanbo Meng https://www.ebm-journal.org/articles/10.3389/ebm.2026.11246 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11246 <![CDATA[Extracellular vesicles for abdominal aortic aneurysm: mechanisms, therapeutic potential, and translational challenges]]> 2026-08-28T00:00:00Z Review Huibo MaZongyou XieYihang CaiFangda LiJianqiang WuYuehong Zheng https://www.ebm-journal.org/articles/10.3389/ebm.2026.11146 https://www.ebm-journal.org/articles/10.3389/ebm.2026.11146 <![CDATA[The interaction between oxidative stress and Schwann cells]]> 2026-08-27T00:00:00Z Review Sihan YangZijun ZhangQing LiaoQipeng OuyangYongyou YeWei LuZhendong Jiang