Experimental Biology and Medicine | Genomics, Proteomics and Bioinformatics section | New and Recent Articles https://www.ebm-journal.org/journals/experimental-biology-and-medicine/sections/genomics-proteomics-and-bioinformatics RSS Feed for Genomics, Proteomics and Bioinformatics section in the Experimental Biology and Medicine journal | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-04-06T17:47:27.576+00:00 60 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10929 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10929 <![CDATA[Global MyoG research 2004–2024: a bibliometric analysis of trends and translational implications]]> 2026-03-05T00:00:00Z Original Research Luoming HuWeizhong ZhuangWeimin ChenSong YangShuo ChenXin WangQiang GaoJimei Chen https://www.ebm-journal.org/articles/10.3389/ebm.2026.10709 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10709 <![CDATA[Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validation]]> 2026-03-02T00:00:00Z Original Research Xiqin WangChrismis Novalinda GintingWilliam Leslie https://www.ebm-journal.org/articles/10.3389/ebm.2026.10894 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10894 <![CDATA[The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals]]> 2026-02-23T00:00:00Z Brief Communication Inna BurakovaYuliya SmirnovaPolina MorozovaSvetlana PogorelovaOlga KryukovaTatiana KislovaOlga KorneevaMikhail Syromyatnikov https://www.ebm-journal.org/articles/10.3389/ebm.2026.10745 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10745 <![CDATA[Poliovirus receptor (PVR) expression as a predictor of relapse in colorectal cancer: bioinformatics and virtual screening]]> 2026-02-13T00:00:00Z Original Research Sulaiman S. AlhudaithiMuhamed Hamza R. SalihZaid H. AlHusseiniSarah M. AlmufadhiliNoura AlelayaniAhmed H. BakheitHamad M. AlkahtaniHanadi H. AsiriAli A. AlshamraniAli R. AlhoshaniMoureq R. AlotaibiHomood M. As Sobeai https://www.ebm-journal.org/articles/10.3389/ebm.2026.10893 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10893 <![CDATA[Expanding the clinical and genetic spectrum of RHO-associated retinitis pigmentosa]]> 2026-02-04T00:00:00Z Original Research Rebeca A. S. AmaralOlivia A. ZinRosane G. ResendeDebora N. MoraesMariana V. SallesGabriela D. RodriguesFabiana L. MottaJuliana M. F. Sallum T; c.937-2A>T, c.272_283del, and c.530+1G>C) were identified. The majority of cases involved missense variants. The most prevalent variant was c.551A>G, p.(Gln184Arg), which was identified in seven patients (21%) from four families. One patient presented with the splice donor variant c.530+1G>C in the homozygous state, which was classified as pathogenic. Thirty-two patients presented with a generalized RP phenotype, and six patients were diagnosed with sector RP. This study provides information on the clinical and genetic features of RHO-associated RP in the Brazilian population, expanding the spectrum of RHO gene disease-causing variant frequencies.]]> https://www.ebm-journal.org/articles/10.3389/ebm.2025.10866 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10866 <![CDATA[Integrated tear proteomics define the molecular blueprint of corneal epithelial repair]]> 2026-02-02T00:00:00Z Original Research Nadege FeretMarilou DecouduJerome VialaretChristophe HirtzKarine LoulierVincent DaienFrederic Michon https://www.ebm-journal.org/articles/10.3389/ebm.2026.10906 https://www.ebm-journal.org/articles/10.3389/ebm.2026.10906 <![CDATA[Causal effects of antibody-mediated immunity to pathogens on five ophthalmic diseases: a Mendelian randomization study]]> 2026-01-30T00:00:00Z Original Research Liduo PanJian DengJianli YangMeng WangZheng ChenTao WangYonghao Li https://www.ebm-journal.org/articles/10.3389/ebm.2025.10771 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10771 <![CDATA[Altered MCF2L-AS1 expression and correlation with the prognosis of diabetic nephropathy]]> 2026-01-22T00:00:00Z Original Research Nastaran InjinariMorteza HadizadehNasim NamiranianSeyed Mehdi KalantarAli Dehghani FiroozabadiSamira Asadollahi https://www.ebm-journal.org/articles/10.3389/ebm.2025.10776 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10776 <![CDATA[Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response]]> 2026-01-14T00:00:00Z Original Research Feifei KongJiawei FengHaixia ShanYoulong ZhuLing-Jun Zhu https://www.ebm-journal.org/articles/10.3389/ebm.2025.10864 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10864 <![CDATA[Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study]]> 2026-01-12T00:00:00Z Original Research Daniel de Almeida BorgesMarcos Rodrigo AlborghettiRomenia Ramos DominguesAdriana Franco Paes LemeMônica Alves https://www.ebm-journal.org/articles/10.3389/ebm.2025.10533 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10533 <![CDATA[TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis]]> 2025-10-15T00:00:00Z Original Research Marya ObeidatSaleh TadrosBatool IsmailAyah Al-Khaldi https://www.ebm-journal.org/articles/10.3389/ebm.2025.10610 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10610 <![CDATA[Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis]]> 2025-10-15T00:00:00Z Original Research Dongdong JinJie SunWei ZhangMingxuan ZhangChengfang Li https://www.ebm-journal.org/articles/10.3389/ebm.2025.10599 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10599 <![CDATA[Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications]]> 2025-10-01T00:00:00Z Original Research Hai GaoTing WuJihui XueJing LiuDongmei WenGuanwei Huang https://www.ebm-journal.org/articles/10.3389/ebm.2025.10632 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10632 <![CDATA[Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer]]> 2025-09-25T00:00:00Z Original Research Xinya LuZhen ChenYing Shao https://www.ebm-journal.org/articles/10.3389/ebm.2025.10623 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10623 <![CDATA[Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma]]> 2025-09-19T00:00:00Z Original Research Lina YangJingyu HaiJiayi LiuShaohua ShenLin SuJuan Sun https://www.ebm-journal.org/articles/10.3389/ebm.2025.10430 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10430 <![CDATA[RNA binding proteins potentially regulate alternative splicing of immune-related genes during the progression of coronary artery disease]]> 2025-08-29T00:00:00Z Original Research Yulin MiaoLei WangGang ZhaoWei GouShan ChenChao DingZongxin LiFengli Gao https://www.ebm-journal.org/articles/10.3389/ebm.2025.10452 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10452 <![CDATA[Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism]]> 2025-08-29T00:00:00Z Original Research Shuzhen ZhaoXinyan ZhangYanqiu MiaoXueya GaoQiuhua WanWei QiuHaixia SiYingjie HanXiao DuYuanyuan FengLianhua LiuYuqing Chen https://www.ebm-journal.org/articles/10.3389/ebm.2025.10544 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10544 <![CDATA[Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study]]> 2025-08-04T00:00:00Z Original Research Chen LiYicheng LuMingxuan ChenQing ZhangZhe ZhangWenqun XiWeihua Yang https://www.ebm-journal.org/articles/10.3389/ebm.2025.10593 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10593 <![CDATA[Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing]]> 2025-07-17T00:00:00Z Original Research Eleonora SabettaKarin RallmannJonas BergquistPille TabaAbigail L. PfaffBal Hari PoudelDavide FerrariMassimo LocatelliSulev Kõks https://www.ebm-journal.org/articles/10.3389/ebm.2025.10128 https://www.ebm-journal.org/articles/10.3389/ebm.2025.10128 <![CDATA[An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing]]> 2025-07-11T00:00:00Z Original Research Li-Li ZhangZhe WangYing ZhouDai-Yang LiXiao-Nian TuYu-Xia LiKe-Ming DuZhong-Zheng Zheng