Experimental Biology and Medicine

Review

Published on 19 Dec 2025

Chimeric antigen receptor natural killer cell therapy for solid tumors: mechanisms, clinical progress, and strategies to overcome the tumor microenvironment

Yu Xiang
Jiayi Dong
Lijuan Shao
Size Chen

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10841

132 views

Original Research

Published on 18 Dec 2025

Diet–lifestyle oxidative balance in relation to cardiometabolic multimorbidity: findings from the national health and nutrition examination survey

Wenrui Shi
Yu Zhao
Jieun Park
Wan Chen

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10824

261 views

Original Research

Published on 12 Dec 2025

Protective effects of berberine-loaded chitosan/solid lipid nanoparticles in streptozotocin-induced gestational diabetes mellitus rats

Yu Liu
Shaik Althaf Hussain
Hua Yue

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10749

229 views

Review

Published on 08 Dec 2025

Peripheral artery disease and local drug delivery: a review of disease pathology and drug delivery systems for therapy below the knee

Nicole M. Akers
Tammy R. Dugas

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10754

385 views

Original Research

Published on 08 Dec 2025

Clinical data comparison for FDA-approved gene therapies in sickle cell disease

Alexis Leonard
Julie Kanter

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10806

379 views

Brief Communication

Published on 03 Dec 2025

ApoE COG 133 mimetic peptide improves survival, infection burden, and Clostridioides difficile toxin-A-induced intestinal damage in mice

Orleâncio G. R. de Azevedo
Jae H. Shin
Rosemayre S. Freire
Gabriella C. V. Ciurleo
Gerly A. C. Brito
Michael P. Vitek
Richard L. Guerrant
Reinaldo B. Oriá
Cirle A. Warren

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10638

375 views

Original Research

Published on 03 Dec 2025

Mapping microglial mechanisms in Alzheimer’s disease: a comprehensive analysis

Xiaofang Wang
Yuqing Guo
Yonghan Zha
Shuling Wang
Weihua Yang
Qianfang Jia

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10808

406 views

Original Research

Published on 27 Nov 2025

Characterisation of the function of a lncRNA containing SINE-VNTR-Alu 67 to regulate the genes at the MAPT locus

Kynen Piacentini
Alexander Fröhlich
Abigail Pfaff
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10805

468 views

Original Research

Published on 13 Nov 2025

The causal relationship between obstructive sleep apnea and otitis media: a bidirectional Mendelian randomization study

Ruixin Guo
Yifan Zhang
Yijie Chen
Wenqi Sha
Wanyi Kou
Chensi Xu
Yuran Lei
Ningrui Zhang
Liu Yang
Yun Guo

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10540

1,982 views

Original Research

Published on 07 Nov 2025

Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice

Sandip Godse
Lina Zhou
Namita Sinha
Mohd Salman
Tauheed Ishrat
Santosh Kumar

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10758

3,037 views

Original Research

Published on 21 Oct 2025

Bioinformatics-based screening and validation of ferroptosis-related genes in sepsis and type 2 diabetes mellitus

Heng Xiao
Zhonghua Ding
Cheng Liu
Xu He
Yanyan Tao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10612

3,820 views

Original Research

Published on 15 Oct 2025

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

Marya Obeidat
Saleh Tadros
Batool Ismail
Ayah Al-Khaldi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10533

3,385 views

Original Research

Published on 15 Oct 2025

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

Dongdong Jin
Jie Sun
Wei Zhang
Mingxuan Zhang
Chengfang Li

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10610

3,766 views

Original Research

Published on 03 Oct 2025

Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing

Donglin Yu
Qianghong Tian
Junxi Shen
Leyao Fang
Zhoujin Tan
Ying Cai

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10725

4,297 views

Original Research

Published on 01 Oct 2025

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

Hai Gao
Ting Wu
Jihui Xue
Jing Liu
Dongmei Wen
Guanwei Huang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10599

3,459 views
1 citation

Original Research

Published on 01 Oct 2025

High-fidelity, personalized cardiac modeling via AI-driven 3D reconstruction and embedded silicone rubber printing

Xuefang Wang
Yixin Li
Zhiqi Liang
Ruxu Du
Ting Song

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10756

3,333 views

Original Research

Published on 30 Sep 2025

Therapeutic effects of mesenchymal stromal cell secretome in liver fibrosis with acute lung injury

Ane Caroline Ribeiro Novaes Martins
Karina Ribeiro Silva
Anna Carolina de Souza Pereira
Gustavo Claudino Paris
Ana Lúcia Rosa Nascimento
Verônica Aiceles
Erika Afonso Costa Cortez
Alessandra Alves Thole
Simone Nunes de Carvalho

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10782

2,202 views

Original Research

Published on 25 Sep 2025

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

Xinya Lu
Zhen Chen
Ying Shao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10632

3,912 views

Review

Published on 23 Sep 2025

Platelet-rich plasma in peripheral nerve injury repair: a comprehensive review of mechanisms, clinical applications, and therapeutic potential

Kai Shang
Yang Liu
Abdul Qadeer

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10746

2,838 views

Original Research

Published on 22 Sep 2025

Variational autoencoder enhanced analysis of energy metabolism and autophagy in exercising cardiomyocytes

Liquan Chen
Yun Yang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10489

986 views

Original Research

Published on 19 Sep 2025

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

Lina Yang
Jingyu Hai
Jiayi Liu
Shaohua Shen
Lin Su
Juan Sun

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10623

2,026 views

Original Research

Published on 18 Sep 2025

A case study of long-term disease burden in a rural community near an open burn facility

Arundhati Bakshi
Liana Baconguis
Md Abdullah Al-Mamun
Qingzhao Yu
Jennifer Richmond-Bryant
Stephania A. Cormier

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10710

2,292 views

Review

Published on 03 Sep 2025

Unraveling the pharmacological and therapeutic potential of Ranolazine beyond antianginal drug use: a new insight

Dhirendra Singh
Joy Awulika Oladimeji-Salami
Abidemi James Akindele

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10604

4,467 views

Original Research

Published on 29 Aug 2025

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism

Shuzhen Zhao
Xinyan Zhang
Yanqiu Miao
Xueya Gao
Qiuhua Wan
Wei Qiu
Haixia Si
Yingjie Han
Xiao Du
Yuanyuan Feng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10452

4,784 views

47,764 Publications

volumes

Volume 250 - 2025

Chimeric antigen receptor natural killer cell therapy for solid tumors: mechanisms, clinical progress, and strategies to overcome the tumor microenvironment

Diet–lifestyle oxidative balance in relation to cardiometabolic multimorbidity: findings from the national health and nutrition examination survey

Protective effects of berberine-loaded chitosan/solid lipid nanoparticles in streptozotocin-induced gestational diabetes mellitus rats

Peripheral artery disease and local drug delivery: a review of disease pathology and drug delivery systems for therapy below the knee

Clinical data comparison for FDA-approved gene therapies in sickle cell disease

ApoE COG 133 mimetic peptide improves survival, infection burden, and Clostridioides difficile toxin-A-induced intestinal damage in mice

Mapping microglial mechanisms in Alzheimer’s disease: a comprehensive analysis

Characterisation of the function of a lncRNA containing SINE-VNTR-Alu 67 to regulate the genes at the MAPT locus

The causal relationship between obstructive sleep apnea and otitis media: a bidirectional Mendelian randomization study

Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice

Bioinformatics-based screening and validation of ferroptosis-related genes in sepsis and type 2 diabetes mellitus

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

High-fidelity, personalized cardiac modeling via AI-driven 3D reconstruction and embedded silicone rubber printing

Therapeutic effects of mesenchymal stromal cell secretome in liver fibrosis with acute lung injury

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

Platelet-rich plasma in peripheral nerve injury repair: a comprehensive review of mechanisms, clinical applications, and therapeutic potential

Variational autoencoder enhanced analysis of energy metabolism and autophagy in exercising cardiomyocytes

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

A case study of long-term disease burden in a rural community near an open burn facility

Unraveling the pharmacological and therapeutic potential of Ranolazine beyond antianginal drug use: a new insight

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism