Experimental Biology and Medicine | Pharmacology and Toxicology

Original Research

Published on 12 Dec 2025

Protective effects of berberine-loaded chitosan/solid lipid nanoparticles in streptozotocin-induced gestational diabetes mellitus rats

in Pharmacology and Toxicology

Yu Liu
Shaik Althaf Hussain
Hua Yue

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10749

Review

Published on 08 Dec 2025

Peripheral artery disease and local drug delivery: a review of disease pathology and drug delivery systems for therapy below the knee

in Pharmacology and Toxicology

Nicole M. Akers
Tammy R. Dugas

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10754

117 views

Original Research

Published on 07 Nov 2025

Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice

in Pharmacology and Toxicology

Sandip Godse
Lina Zhou
Namita Sinha
Mohd Salman
Tauheed Ishrat
Santosh Kumar

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10758

2,492 views

Review

Published on 03 Sep 2025

Unraveling the pharmacological and therapeutic potential of Ranolazine beyond antianginal drug use: a new insight

in Pharmacology and Toxicology

Dhirendra Singh
Joy Awulika Oladimeji-Salami
Abidemi James Akindele

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10604

4,037 views

Original Research

Published on 10 Jun 2025

Comparative electrophysiological study of neuroactive steroid-induced hypnosis in mice: sex and drug-specific differences

in Pharmacology and Toxicology

Abigail Martin
Ian Coulter
Reginald Cox
Douglas F. Covey
Slobodan M. Todorovic
Tamara Timic Stamenic

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10550

1,345 views

Original Research

Published on 09 Jun 2025

Cystamine reduces neurodegeneration and epileptogenesis following soman-induced status epilepticus in rats

in Pharmacology and Toxicology

Abiel K. Biney
Caroline R. Schultz
Michael F. Stone
Donna A. Nguyen
Annie Wang
Marcio de Araujo Furtado
Lucille A. Lumley

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10598

1,180 views
1 citation

Original Research

Published on 19 May 2025

Chronic administration of a cannabis-derived mixture at an antihyperalgesic dose does not significantly enhance hepatotoxicity or the development of metabolic dysfunction-associated steatohepatitis in male mice

in Pharmacology and Toxicology

Kim B. Pedersen
Tomislav Jelesijevic
Tamara M. Morris
Sarah M. Melton
Ashley S. Henderson
John F. Glenn
Gregory J. Davenport
Martin J. J. Ronis
Peter J. Winsauer

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10356

1,598 views

Original Research

Published on 15 May 2025

Involvement of EGFR-AKT signaling in hemin-induced neurotoxicity

in Pharmacology and Toxicology

Hui-Ju Huang
Yang-Jie Tseng
I-Jung Lee
Yu-Li Lo
Anya Maan-Yuh Lin

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10554

1,704 views
1 citation

Original Research

Published on 25 Jul 2024

LM11A-31, a modulator of p75 neurotrophin receptor, suppresses HIV-1 replication and inflammatory response in macrophages

in Pharmacology and Toxicology

Golnoush Mirzahosseini
Namita Sinha
Lina Zhou
Sandip Godse
Sunitha Kodidela
Udai P. Singh
Tauheed Ishrat
Santosh Kumar

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10123

2,285 views
2 citations

Original Research

Published on 31 May 2024

Triptolide decreases podocytes permeability by regulating TET2-mediated hydroxymethylation of ZO-1

in Pharmacology and Toxicology

Yue-Wen Tang
Meng-Ya Jiang
Jia-Wei Cao
Feng Wan

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10051

1,478 views
3 citations

Original Research

Published on 24 May 2024

Different narcotic gases and concentrations for immobilization of ostrich embryos for in-ovo imaging

in Pharmacology and Toxicology

O. Perkas
A. Schmidt
C. Kuehnel
J. Greiser
H. Hermeyer
C. Klingner
M. Freesmeyer
T. Winkens

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10037

967 views
3 citations

Original Research

Published on 22 Apr 2024

Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways

in Pharmacology and Toxicology

Run Ma
Na Xie
Yuanhui Shu
Yafeng Wu
Ping He
Yining Xiang
Yan Zhou
Yuping Wang

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10141

2,705 views
4 citations

Mini Review

Published on 22 Apr 2024

Inhalation exposure-induced toxicity and disease mediated via mTOR dysregulation

in Pharmacology and Toxicology

Akshada Shinde
Jonathan Shannahan

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10135

1,994 views
2 citations