The Physiology and Pathophysiology category welcomes high-quality manuscripts reporting innovative studies that address normal function and/or impact of diseases and treatments on whole organisms, organ systems, organs, cells, organelles, membranes, and biomolecules. Reviews of current topics of interest within the broad scope of physiology and pathophysiology also are welcomed. Examples of topics that fall within this section’s scope include: membrane ion transport and electrophysiology; autonomic control of internal organs; neuro-hormonal signaling mechanisms and their impact on cells and organs; adaptation and maladaptation of internal organs to environmental stresses; mechanisms of ischemic or inflammatory injury of internal organs and novel strategies to prevent such injury; mitochondrial support of cellular function and mediation of cell death vs. survival; physiological regulation of glomerular filtration and renal tubular electrolyte transport; neuroendocrine mechanisms of hypertension; mechanisms of excitotoxicity in brain neurons and its treatment; integrated regulation of cardiopulmonary function during exercise or hypoxia; and the impact of diabetes, volume and electrolyte disorders, immune dysfunction and other disease processes on internal organs, their constituent cells and their functions. The criteria for evaluating manuscripts are: novelty and potential impact of the work; clarity, quality, accuracy and originality of the text, figures and tables; how effectively the methods, experimental design and statistical analyses address the hypotheses; and how well the results support the conclusions.

Associate Editor

Robert T. Mallet, PhD, University of North Texas, USA

Review Editors

R. Todd Alexander, MD/PhD, University of Alberta, Canada

Frantisek Kolar, PhD, Academy of Sciences of the Czech Republic, Czech Republic

Rong Ma, MD/PhD, University of North Texas Health Science Center, USA

Gabor Joseph Tigyi, MD, PhD, University of Tennessee Health Science Center,

Shaw-Jeng Tsai, PhD, National Cheng-Kung University Medical College, Taiwan

Samuel Verges, PhD, Grenoble Alps University, France

Tobias Wang, PhD, Aarhus University, Denmark

Lei Xi, MD, Virginia Commonwealth University, USA

Shaohua Yang, MD, PhD, University of North Texas Health Science Center, USA

Chunyu Zeng, MD, The Third Military Medical University, Chongqing City, China

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