Experimental Biology and Medicine | Genomics, Proteomics and Bioinformatics

Original Research

Published on 02 Mar 2026

Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validation

in Genomics, Proteomics and Bioinformatics

Xiqin Wang
Chrismis Novalinda Ginting
William Leslie

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10709

Brief Communication

Published on 23 Feb 2026

The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals

in Genomics, Proteomics and Bioinformatics

Inna Burakova
Yuliya Smirnova
Polina Morozova
Svetlana Pogorelova
Olga Kryukova
Tatiana Kislova
Olga Korneeva
Mikhail Syromyatnikov

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10894

Original Research

Published on 13 Feb 2026

Poliovirus receptor (PVR) expression as a predictor of relapse in colorectal cancer: bioinformatics and virtual screening

in Genomics, Proteomics and Bioinformatics

Sulaiman S. Alhudaithi
Muhamed Hamza R. Salih
Zaid H. AlHusseini
Sarah M. Almufadhili
Noura Alelayani
Ahmed H. Bakheit
Hamad M. Alkahtani
Hanadi H. Asiri
Ali A. Alshamrani
Ali R. Alhoshani

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10745

337 views

Original Research

Published on 04 Feb 2026

Expanding the clinical and genetic spectrum of RHO-associated retinitis pigmentosa

in Genomics, Proteomics and Bioinformatics

Rebeca A. S. Amaral
Olivia A. Zin
Rosane G. Resende
Debora N. Moraes
Mariana V. Salles
Gabriela D. Rodrigues
Fabiana L. Motta
Juliana M. F. Sallum

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10893

250 views

Original Research

Published on 02 Feb 2026

Integrated tear proteomics define the molecular blueprint of corneal epithelial repair

in Genomics, Proteomics and Bioinformatics

Nadege Feret
Marilou Decoudu
Jerome Vialaret
Christophe Hirtz
Karine Loulier
Vincent Daien
Frederic Michon

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10866

612 views

Original Research

Published on 30 Jan 2026

Causal effects of antibody-mediated immunity to pathogens on five ophthalmic diseases: a Mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Liduo Pan
Jian Deng
Jianli Yang
Meng Wang
Zheng Chen
Tao Wang
Yonghao Li

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10906

216 views

Original Research

Published on 22 Jan 2026

Altered MCF2L-AS1 expression and correlation with the prognosis of diabetic nephropathy

in Genomics, Proteomics and Bioinformatics

Nastaran Injinari
Morteza Hadizadeh
Nasim Namiranian
Seyed Mehdi Kalantar
Ali Dehghani Firoozabadi
Samira Asadollahi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10771

275 views

Original Research

Published on 14 Jan 2026

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

in Genomics, Proteomics and Bioinformatics

Feifei Kong
Jiawei Feng
Haixia Shan
Youlong Zhu
Ling-Jun Zhu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10776

831 views

Original Research

Published on 12 Jan 2026

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

in Genomics, Proteomics and Bioinformatics

Daniel de Almeida Borges
Marcos Rodrigo Alborghetti
Romenia Ramos Domingues
Adriana Franco Paes Leme
Mônica Alves

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10864

343 views

Original Research

Published on 15 Oct 2025

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

in Genomics, Proteomics and Bioinformatics

Marya Obeidat
Saleh Tadros
Batool Ismail
Ayah Al-Khaldi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10533

4,905 views

Original Research

Published on 15 Oct 2025

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

in Genomics, Proteomics and Bioinformatics

Dongdong Jin
Jie Sun
Wei Zhang
Mingxuan Zhang
Chengfang Li

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10610

5,439 views

Original Research

Published on 01 Oct 2025

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

in Genomics, Proteomics and Bioinformatics

Hai Gao
Ting Wu
Jihui Xue
Jing Liu
Dongmei Wen
Guanwei Huang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10599

4,845 views
1 citation

Original Research

Published on 25 Sep 2025

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

in Genomics, Proteomics and Bioinformatics

Xinya Lu
Zhen Chen
Ying Shao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10632

5,496 views

Original Research

Published on 19 Sep 2025

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

in Genomics, Proteomics and Bioinformatics

Lina Yang
Jingyu Hai
Jiayi Liu
Shaohua Shen
Lin Su
Juan Sun

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10623

2,226 views

Original Research

Published on 29 Aug 2025

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism

in Genomics, Proteomics and Bioinformatics

Shuzhen Zhao
Xinyan Zhang
Yanqiu Miao
Xueya Gao
Qiuhua Wan
Wei Qiu
Haixia Si
Yingjie Han
Xiao Du
Yuanyuan Feng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10452

6,418 views

Original Research

Published on 29 Aug 2025

RNA binding proteins potentially regulate alternative splicing of immune-related genes during the progression of coronary artery disease

in Genomics, Proteomics and Bioinformatics

Yulin Miao
Lei Wang
Gang Zhao
Wei Gou
Shan Chen
Chao Ding
Zongxin Li
Fengli Gao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10430

6,015 views

Original Research

Published on 04 Aug 2025

Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Chen Li
Yicheng Lu
Mingxuan Chen
Qing Zhang
Zhe Zhang
Wenqun Xi
Weihua Yang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10544

6,909 views
1 citation

Original Research

Published on 17 Jul 2025

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

in Genomics, Proteomics and Bioinformatics

Eleonora Sabetta
Karin Rallmann
Jonas Bergquist
Pille Taba
Abigail L. Pfaff
Bal Hari Poudel
Davide Ferrari
Massimo Locatelli
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10593

1,972 views

Original Research

Published on 11 Jul 2025

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

in Genomics, Proteomics and Bioinformatics

Li-Li Zhang
Zhe Wang
Ying Zhou
Dai-Yang Li
Xiao-Nian Tu
Yu-Xia Li
Ke-Ming Du
Zhong-Zheng Zheng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10128

1,113 views

Original Research

Published on 03 Jun 2025

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10575

1,504 views
2 citations

Original Research

Published on 29 May 2025

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Vivien J. Bubb
John P. Quinn
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10600

1,581 views

Original Research

Published on 30 Apr 2025

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

in Genomics, Proteomics and Bioinformatics

Yan Zhang
Honggang Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10469

1,415 views
1 citation

Original Research

Published on 15 Jan 2025

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

in Genomics, Proteomics and Bioinformatics

Landi Su
Jingjing Li
Li Qin
Yang Feng
Dingwen Xu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10281

1,419 views

Original Research

Published on 08 Jan 2025

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

in Genomics, Proteomics and Bioinformatics

Sulev Kõks
Karin Rallmann
Mari Muldmaa
Jack Price
Abigail L. Pfaff
Pille Taba

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10401

1,811 views
2 citations

33 articles

articles

Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validation

The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals

Poliovirus receptor (PVR) expression as a predictor of relapse in colorectal cancer: bioinformatics and virtual screening

Expanding the clinical and genetic spectrum of RHO-associated retinitis pigmentosa

Integrated tear proteomics define the molecular blueprint of corneal epithelial repair

Causal effects of antibody-mediated immunity to pathogens on five ophthalmic diseases: a Mendelian randomization study

Altered MCF2L-AS1 expression and correlation with the prognosis of diabetic nephropathy

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism

RNA binding proteins potentially regulate alternative splicing of immune-related genes during the progression of coronary artery disease

Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures