Experimental Biology and Medicine | Genomics, Proteomics and Bioinformatics

Original Research

Published on 14 Jan 2026

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

in Genomics, Proteomics and Bioinformatics

Feifei Kong
Jiawei Feng
Haixia Shan
Youlong Zhu
Ling-Jun Zhu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10776

114 views

Original Research

Published on 12 Jan 2026

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

in Genomics, Proteomics and Bioinformatics

Daniel de Almeida Borges
Marcos Rodrigo Alborghetti
Romenia Ramos Domingues
Adriana Franco Paes Leme
Mônica Alves

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10864

Original Research

Published on 15 Oct 2025

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

in Genomics, Proteomics and Bioinformatics

Marya Obeidat
Saleh Tadros
Batool Ismail
Ayah Al-Khaldi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10533

3,938 views

Original Research

Published on 15 Oct 2025

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

in Genomics, Proteomics and Bioinformatics

Dongdong Jin
Jie Sun
Wei Zhang
Mingxuan Zhang
Chengfang Li

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10610

4,393 views

Original Research

Published on 01 Oct 2025

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

in Genomics, Proteomics and Bioinformatics

Hai Gao
Ting Wu
Jihui Xue
Jing Liu
Dongmei Wen
Guanwei Huang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10599

3,987 views
1 citation

Original Research

Published on 25 Sep 2025

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

in Genomics, Proteomics and Bioinformatics

Xinya Lu
Zhen Chen
Ying Shao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10632

4,458 views

Original Research

Published on 19 Sep 2025

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

in Genomics, Proteomics and Bioinformatics

Lina Yang
Jingyu Hai
Jiayi Liu
Shaohua Shen
Lin Su
Juan Sun

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10623

2,100 views

Original Research

Published on 29 Aug 2025

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism

in Genomics, Proteomics and Bioinformatics

Shuzhen Zhao
Xinyan Zhang
Yanqiu Miao
Xueya Gao
Qiuhua Wan
Wei Qiu
Haixia Si
Yingjie Han
Xiao Du
Yuanyuan Feng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10452

5,383 views

Original Research

Published on 29 Aug 2025

RNA binding proteins potentially regulate alternative splicing of immune-related genes during the progression of coronary artery disease

in Genomics, Proteomics and Bioinformatics

Yulin Miao
Lei Wang
Gang Zhao
Wei Gou
Shan Chen
Chao Ding
Zongxin Li
Fengli Gao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10430

5,180 views

Original Research

Published on 04 Aug 2025

Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Chen Li
Yicheng Lu
Mingxuan Chen
Qing Zhang
Zhe Zhang
Wenqun Xi
Weihua Yang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10544

6,013 views

Original Research

Published on 17 Jul 2025

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

in Genomics, Proteomics and Bioinformatics

Eleonora Sabetta
Karin Rallmann
Jonas Bergquist
Pille Taba
Abigail L. Pfaff
Bal Hari Poudel
Davide Ferrari
Massimo Locatelli
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10593

1,711 views

Original Research

Published on 11 Jul 2025

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

in Genomics, Proteomics and Bioinformatics

Li-Li Zhang
Zhe Wang
Ying Zhou
Dai-Yang Li
Xiao-Nian Tu
Yu-Xia Li
Ke-Ming Du
Zhong-Zheng Zheng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10128

963 views

Original Research

Published on 03 Jun 2025

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10575

1,342 views
2 citations

Original Research

Published on 29 May 2025

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Vivien J. Bubb
John P. Quinn
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10600

1,462 views

Original Research

Published on 30 Apr 2025

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

in Genomics, Proteomics and Bioinformatics

Yan Zhang
Honggang Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10469

1,276 views
1 citation

Original Research

Published on 15 Jan 2025

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

in Genomics, Proteomics and Bioinformatics

Landi Su
Jingjing Li
Li Qin
Yang Feng
Dingwen Xu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10281

1,362 views

Original Research

Published on 08 Jan 2025

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

in Genomics, Proteomics and Bioinformatics

Sulev Kõks
Karin Rallmann
Mari Muldmaa
Jack Price
Abigail L. Pfaff
Pille Taba

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10401

1,612 views
2 citations

Original Research

Published on 23 Sep 2024

Integrated multi-omics profiling reveals the ZZZ3/CD70 axis is a super-enhancer-driven regulator of diffuse large B-cell lymphoma cell-natural killer cell interactions

in Genomics, Proteomics and Bioinformatics

Xi Li
Juya Cui
Liao Wang
Caihong Cao
Hu Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10155

3,086 views

Correction

Published on 19 Sep 2024

Corrigendum: Genome-wide association study identifying variants related to performance and injury in high-performance athletes

in Genomics, Proteomics and Bioinformatics

Jay R. Ebert
Agnes Magi
Eve Unt
Ele Prans
David J. Wood
Sulev Koks

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10348

997 views

Review

Published on 18 Sep 2024

Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells

in Genomics, Proteomics and Bioinformatics

Wen-Bin Liu
Damian Fermin
An-Long Xu
Jeffrey B. Kopp
Qihe Xu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10167

4,446 views

Original Research

Published on 22 Jul 2024

The causal relationship between autoimmune diseases and rhinosinusitis, and the mediating role of inflammatory proteins: a Mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Yanjing Liang
Shao Yin
Xiangyan Chen
Chengen Li
Qiu Chen

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10196

2,747 views
7 citations

Original Research

Published on 09 Jul 2024

Identification of potential biomarkers for cerebral palsy and the development of prediction models

in Genomics, Proteomics and Bioinformatics

Haoyang Zheng
Duo Zhang
Yong Gan
Zesheng Peng
Yuyi Wu
Wei Xiang

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10101

2,021 views
4 citations

Original Research

Published on 27 Jun 2024

Bioinformatics and systems biology approach to identify the pathogenetic link of neurological pain and major depressive disorder

in Genomics, Proteomics and Bioinformatics

Jinjing Hu
Jia Fu
Yuxin Cai
Shuping Chen
Mengjian Qu
Lisha Zhang
Weichao Fan
Ziyi Wang
Qing Zeng
Jihua Zou

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10129

2,391 views
1 citation

Original Research

Published on 20 Jun 2024

The whole transcriptome analysis using FFPE and fresh tissue samples identifies the molecular fingerprint of osteosarcoma

in Genomics, Proteomics and Bioinformatics

Bal Hari Poudel
Sulev Koks

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10161

2,190 views
19 citations

26 articles

articles

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism

RNA binding proteins potentially regulate alternative splicing of immune-related genes during the progression of coronary artery disease

Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

Integrated multi-omics profiling reveals the ZZZ3/CD70 axis is a super-enhancer-driven regulator of diffuse large B-cell lymphoma cell-natural killer cell interactions

Corrigendum: Genome-wide association study identifying variants related to performance and injury in high-performance athletes

Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells

The causal relationship between autoimmune diseases and rhinosinusitis, and the mediating role of inflammatory proteins: a Mendelian randomization study

Identification of potential biomarkers for cerebral palsy and the development of prediction models

Bioinformatics and systems biology approach to identify the pathogenetic link of neurological pain and major depressive disorder

The whole transcriptome analysis using FFPE and fresh tissue samples identifies the molecular fingerprint of osteosarcoma