Experimental Biology and Medicine

Original Research

Published on 14 Jan 2026

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

Feifei Kong
Jiawei Feng
Haixia Shan
Youlong Zhu
Ling-Jun Zhu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10776

120 views

Original Research

Published on 14 Jan 2026

The correlation between pro- and anti-inflammatory cytokines and anti-spike IgG antibody responses induced by the SARS-CoV-2 coronavirus vaccine

Mustafa Abdulkareem Salman
Thowiba Yousif Jameel
Abdurrahman Ayvaz
Ahmed Rushdi Abdullah

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10849

166 views

Original Research

Published on 13 Jan 2026

Inflammatory indicators derived from complete blood counts in relation to osteoarthritis prevalence: findings from the NHANES 2007–2020 cross-sectional survey

Zimo Ye
Tianran Zhao
Xinlin Huang
Yingxue Song
Luyi Cheng
Yunyi Liu
Mingde Qiu
Ruke Long
Weihao Chen
Yu Wang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10815

339 views

Original Research

Published on 12 Jan 2026

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

Daniel de Almeida Borges
Marcos Rodrigo Alborghetti
Romenia Ramos Domingues
Adriana Franco Paes Leme
Mônica Alves

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10864

Review

Published on 07 Jan 2026

Neutrophil extracellular traps: emerging drivers and therapeutic targets in abdominal aortic aneurysm pathogenesis

Xinyi Lyu
Qi Liu
Jiahao Shi
Yajun Chen
Xianpeng Dai

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10781

172 views

Original Research

Published on 06 Jan 2026

LncRNA HOTAIR promotes LPS-induced inflammatory responses by activating the NF-κB pathway

Fengqing Zhu
Zexun Mo
Wuzhou Lin
Cheng Sun
Xiaomei Huang
Meifeng Ye
Hua He
Yujun Li
Kangwei Wang
Juan Zhu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10766

465 views

Review

Published on 19 Dec 2025

Chimeric antigen receptor natural killer cell therapy for solid tumors: mechanisms, clinical progress, and strategies to overcome the tumor microenvironment

Yu Xiang
Jiayi Dong
Lijuan Shao
Size Chen

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10841

752 views

Original Research

Published on 18 Dec 2025

Diet–lifestyle oxidative balance in relation to cardiometabolic multimorbidity: findings from the national health and nutrition examination survey

Wenrui Shi
Yu Zhao
Jieun Park
Wan Chen

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10824

1,309 views

Original Research

Published on 12 Dec 2025

Protective effects of berberine-loaded chitosan/solid lipid nanoparticles in streptozotocin-induced gestational diabetes mellitus rats

Yu Liu
Shaik Althaf Hussain
Hua Yue

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10749

647 views

Review

Published on 12 Dec 2025

Beginning of a new era of synthetic messenger RNA therapeutics: Comprehensive insights on mRNA drug design, development and applications

Saumya Nishanga Heendeniya
Suxiang Chen
Saadia Bhatti
Qurat Ul Ain Zahra
Kamal Rahimizadeh
Bal Hari Poudel
Stephen D. Wilton
Rakesh N. Veedu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10784

566 views

Review

Published on 08 Dec 2025

Peripheral artery disease and local drug delivery: a review of disease pathology and drug delivery systems for therapy below the knee

Nicole M. Akers
Tammy R. Dugas

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10754

752 views

Original Research

Published on 08 Dec 2025

Clinical data comparison for FDA-approved gene therapies in sickle cell disease

Alexis Leonard
Julie Kanter

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10806

678 views

Brief Communication

Published on 03 Dec 2025

ApoE COG 133 mimetic peptide improves survival, infection burden, and Clostridioides difficile toxin-A-induced intestinal damage in mice

Orleâncio G. R. de Azevedo
Jae H. Shin
Rosemayre S. Freire
Gabriella C. V. Ciurleo
Gerly A. C. Brito
Michael P. Vitek
Richard L. Guerrant
Reinaldo B. Oriá
Cirle A. Warren

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10638

513 views

Original Research

Published on 03 Dec 2025

Mapping microglial mechanisms in Alzheimer’s disease: a comprehensive analysis

Xiaofang Wang
Yuqing Guo
Yonghan Zha
Shuling Wang
Weihua Yang
Qianfang Jia

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10808

739 views

Original Research

Published on 27 Nov 2025

Characterisation of the function of a lncRNA containing SINE-VNTR-Alu 67 to regulate the genes at the MAPT locus

Kynen Piacentini
Alexander Fröhlich
Abigail Pfaff
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10805

617 views

Original Research

Published on 13 Nov 2025

The causal relationship between obstructive sleep apnea and otitis media: a bidirectional Mendelian randomization study

Ruixin Guo
Yifan Zhang
Yijie Chen
Wenqi Sha
Wanyi Kou
Chensi Xu
Yuran Lei
Ningrui Zhang
Liu Yang
Yun Guo

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10540

2,580 views

Original Research

Published on 07 Nov 2025

Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice

Sandip Godse
Lina Zhou
Namita Sinha
Mohd Salman
Tauheed Ishrat
Santosh Kumar

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10758

3,645 views

Original Research

Published on 21 Oct 2025

Bioinformatics-based screening and validation of ferroptosis-related genes in sepsis and type 2 diabetes mellitus

Heng Xiao
Zhonghua Ding
Cheng Liu
Xu He
Yanyan Tao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10612

4,426 views

Original Research

Published on 15 Oct 2025

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

Marya Obeidat
Saleh Tadros
Batool Ismail
Ayah Al-Khaldi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10533

3,964 views

Original Research

Published on 15 Oct 2025

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

Dongdong Jin
Jie Sun
Wei Zhang
Mingxuan Zhang
Chengfang Li

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10610

4,462 views

Original Research

Published on 03 Oct 2025

Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing

Donglin Yu
Qianghong Tian
Junxi Shen
Leyao Fang
Zhoujin Tan
Ying Cai

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10725

4,933 views

Original Research

Published on 01 Oct 2025

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

Hai Gao
Ting Wu
Jihui Xue
Jing Liu
Dongmei Wen
Guanwei Huang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10599

4,015 views
1 citation

Original Research

Published on 01 Oct 2025

High-fidelity, personalized cardiac modeling via AI-driven 3D reconstruction and embedded silicone rubber printing

Xuefang Wang
Yixin Li
Zhiqi Liang
Ruxu Du
Ting Song

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10756

3,910 views

Original Research

Published on 30 Sep 2025

Therapeutic effects of mesenchymal stromal cell secretome in liver fibrosis with acute lung injury

Ane Caroline Ribeiro Novaes Martins
Karina Ribeiro Silva
Anna Carolina de Souza Pereira
Gustavo Claudino Paris
Ana Lúcia Rosa Nascimento
Verônica Aiceles
Erika Afonso Costa Cortez
Alessandra Alves Thole
Simone Nunes de Carvalho

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10782

2,308 views

47,771 Publications

volumes

Volume 250 - 2025

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

The correlation between pro- and anti-inflammatory cytokines and anti-spike IgG antibody responses induced by the SARS-CoV-2 coronavirus vaccine

Inflammatory indicators derived from complete blood counts in relation to osteoarthritis prevalence: findings from the NHANES 2007–2020 cross-sectional survey

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

Neutrophil extracellular traps: emerging drivers and therapeutic targets in abdominal aortic aneurysm pathogenesis

LncRNA HOTAIR promotes LPS-induced inflammatory responses by activating the NF-κB pathway

Chimeric antigen receptor natural killer cell therapy for solid tumors: mechanisms, clinical progress, and strategies to overcome the tumor microenvironment

Diet–lifestyle oxidative balance in relation to cardiometabolic multimorbidity: findings from the national health and nutrition examination survey

Protective effects of berberine-loaded chitosan/solid lipid nanoparticles in streptozotocin-induced gestational diabetes mellitus rats

Beginning of a new era of synthetic messenger RNA therapeutics: Comprehensive insights on mRNA drug design, development and applications

Peripheral artery disease and local drug delivery: a review of disease pathology and drug delivery systems for therapy below the knee

Clinical data comparison for FDA-approved gene therapies in sickle cell disease

ApoE COG 133 mimetic peptide improves survival, infection burden, and Clostridioides difficile toxin-A-induced intestinal damage in mice

Mapping microglial mechanisms in Alzheimer’s disease: a comprehensive analysis

Characterisation of the function of a lncRNA containing SINE-VNTR-Alu 67 to regulate the genes at the MAPT locus

The causal relationship between obstructive sleep apnea and otitis media: a bidirectional Mendelian randomization study

Curcumin-enhanced elvitegravir therapy mitigates neuroinflammation and cognitive deficits in EcoHIV mice

Bioinformatics-based screening and validation of ferroptosis-related genes in sepsis and type 2 diabetes mellitus

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

High-fidelity, personalized cardiac modeling via AI-driven 3D reconstruction and embedded silicone rubber printing

Therapeutic effects of mesenchymal stromal cell secretome in liver fibrosis with acute lung injury